Gender Matters in Drug Response

A new study has found that women respond better than men to certain antipsychotic drugs. The Schizophrenia Outpatient Health Outcomes study compared responses to medication of around 4500 men and 3500 women from 10 European countries, in terms of reduced symptoms and improved quality of life. Women had more reduction of symptoms and more improved quality of life compared to men taking clozapine (Clozaril) and the typical antipsychotics. On olanzapine (Zyprexa), women had a more improved quality of life compared to men, although men and women experienced similar reductions in their symptoms. The study didn't find gender differences in response to risperdone (Risperdal). This study emphasizes that individuals respond differently to medications for many reasons. It's important to work with your doctors to find the medications that work best for you.